Nucleadyn polymerised polynucleotide gel at Berkshire Aesthetics

Nucleadyn eye rejuvenation treatment in Maidenhead

Nucleadyn is a targeted treatment for the delicate eye area, addressing dark circles, puffiness and fine lines using bioactive compounds derived from the Alpinia Nigra plant. At Berkshire Aesthetics in Maidenhead, suitability is assessed clinically and we focus on safe, realistic outcomes for periorbital rejuvenation.

Book Consultation
Book a Consultation

Clinically reviewed by

Dr Selena LangdonMedical Director, MBBS

GMC 6159259

Last reviewed:

Information is general and not a substitute for a medical consultation. Suitability is confirmed during assessment.

Why we start with a consultation

Every treatment begins with a medical assessment. We need to understand your medical history, current health, skin condition and concerns before prescribing any procedure. This protects your safety and ensures the treatment is clinically appropriate for you.

During your consultation, Dr Langdon will explain what the treatment can realistically achieve, any risks specific to you, and whether an alternative might be more appropriate.

All bookings are subject to our Booking Conditions.

Doctor-led approach

Clinical overview

Nucleadyn is a specialist eye-area treatment that uses bioactive compounds derived from the Alpinia Nigra plant to target common periorbital concerns including dark circles, puffiness and fine lines. The treatment works by improving microcirculation around the eye area, stimulating collagen and elastin production, and delivering antioxidant and anti-inflammatory benefits. This helps to address the underlying causes of tired-looking eyes — not just the surface appearance. We use Nucleadyn selectively for patients whose primary concern is the periorbital area and who want targeted improvement without invasive intervention. The eye area is particularly delicate, so we assess each patient's suitability carefully during consultation — including skin condition, medical history, expectations and whether Nucleadyn or an alternative approach would be the most effective and safest option.

Key Benefits

  • Targeted treatment specifically designed for the delicate periorbital (eye) area
  • Improves microcirculation to help reduce dark circles and puffiness
  • Stimulates collagen and elastin production for firmer, smoother under-eye skin
  • Contains antioxidant and anti-inflammatory bioactive compounds from Alpinia Nigra
  • Non-invasive approach with minimal downtime

Suitable For

  • Dark circles under the eyes where improved microcirculation may help
  • Puffiness or fluid retention around the eye area
  • Fine lines and crepey skin around the eyes where collagen stimulation is beneficial
  • Patients who want a targeted, non-invasive eye treatment
  • Those seeking gradual improvement in the periorbital area

Not Suitable For

  • Active infection, inflammation or broken skin around the eye area
  • Pregnancy or breastfeeding
  • Known allergy to any of the bioactive compounds (discussed during consultation)
  • Severe volume loss under the eyes where structural support with filler may be more appropriate
  • Anyone expecting instant or dramatic results from a single session

Final suitability is confirmed during a medical consultation and assessment.

When we don't recommend it

  • If under-eye hollowing or tear trough volume loss is the primary concern — dermal fillers or other approaches may be more effective and we will discuss alternatives.
  • If there is active inflammation or skin breakdown around the eyes — treatment should be delayed until the area has healed.
  • If dark circles are caused by pigmentation rather than circulatory issues — we may recommend alternative treatments better suited to your specific cause.
  • If expectations are for a dramatic transformation — Nucleadyn provides gradual, subtle improvement and we will set realistic expectations during consultation.
  • If a combination approach would produce a safer or more effective result — for example, combining with polynucleotides or skincare optimisation.

What Happens During Treatment

  1. 1Clinical consultation and suitability assessment, including your eye-area concerns, medical history and goals
  2. 2Discussion of expected outcomes, realistic timelines, limitations, risks and alternatives
  3. 3The periorbital area is carefully prepared and the Nucleadyn treatment is applied to the targeted zone
  4. 4Treatment is gentle and focused on the delicate eye area
  5. 5Post-treatment checks and aftercare guidance specific to the periorbital area

Downtime & Aftercare

  • Minimal downtime — mild redness or sensitivity around the eye area may occur and typically settles quickly
  • Avoid rubbing or touching the treated area for the remainder of the day
  • Avoid heavy exercise, saunas and swimming for 24 hours
  • Apply SPF and avoid direct sun exposure to the treated area
  • If you notice unexpected or worsening symptoms, contact the clinic for advice

Results Timeline

  • A course of treatments is typically recommended for optimal results — your plan is tailored during consultation.
  • Improvement is gradual, with changes in microcirculation, collagen production and skin quality developing over several weeks.
  • We review outcomes and discuss whether maintenance or complementary treatments are appropriate.

How Long Results May Last

  • Duration of results varies by individual, baseline skin condition and lifestyle factors.
  • Maintenance treatments may be recommended to sustain improvements in the periorbital area.

Individual results vary. View our results and photography standards

Risks & Side Effects

Common, Usually Temporary

  • Mild redness or sensitivity around the eye area (usually settles within hours)
  • Slight swelling or puffiness immediately after treatment (temporary)
  • Minor tenderness in the treated area

Rare but Serious

  • Prolonged swelling or irritation around the eyes (uncommon; contact the clinic if concerned)
  • Allergic reaction to bioactive compounds (rare; discussed during consultation)
  • Any unexpected or worsening symptoms should be assessed promptly

When to Contact Us Urgently

  • Persistent swelling, redness or discomfort around the eye area that does not settle
  • Any significant irritation, visual changes or skin reaction
  • Any symptoms that concern you or are different from what was discussed

Frequently Asked Questions

Nucleadyn is specifically designed for the eye area and targets dark circles, puffiness and fine lines. It works by improving microcirculation and stimulating collagen and elastin production around the periorbital zone.
Alpinia Nigra is a plant from which the bioactive compounds in Nucleadyn are derived. These compounds have antioxidant and anti-inflammatory properties that support periorbital skin health and rejuvenation.
Not always. Dark circles can have different causes including poor microcirculation, pigmentation, volume loss or genetics. During consultation, we assess the underlying cause and recommend Nucleadyn only where it is likely to be effective.
A course of treatments is typically recommended. The number of sessions depends on your individual concerns and how your skin responds. This is discussed and planned during your consultation.
Downtime is minimal. Mild redness or sensitivity around the eye area may occur and usually settles within a few hours. Most patients return to normal activities the same day.
Yes. Nucleadyn can be combined with other treatments such as polynucleotides or Plinest where appropriate. Combination plans are discussed during consultation and recommended only when they are likely to improve outcomes.
Nucleadyn may not be appropriate if you have active infection around the eyes, are pregnant or breastfeeding, or if your primary concern is significant under-eye volume loss where dermal fillers may be more suitable. Suitability is confirmed during consultation.
We provide transparent pricing at consultation, tailored to your treatment plan. Costs depend on the number of sessions recommended and the extent of your periorbital concerns.
The treatment is gentle and designed for the delicate eye area. Most patients find it comfortable with minimal discomfort. Any sensitivity is temporary and settles quickly after the session.
We assess your eye-area concerns, identify the underlying cause of dark circles or puffiness, review your medical history, and discuss whether Nucleadyn is the most effective option for you.
Yes. Most patients return to normal activities the same day. Mild redness or sensitivity around the eyes may occur but usually settles within a few hours of treatment.

Quick Facts

Treatment Time

30–45 minutes per session

Downtime

Minimal — mild redness or sensitivity for a few hours

Results Visible

Gradual improvement over a course of treatments

Sessions

Course recommended (individualised during consultation)

Guide Price

From £250 – £400

Per session

Final price confirmed at consultation

Delivered by

Dr Selena Langdon — Medical Director

MBBS, Injectable Trainer, JCCP Ambassador

Why Berkshire Aesthetics

  • Doctor-led clinic — all treatments clinically overseen by Dr Selena Langdon (MBBS)
  • CQC registered — view our registration
  • Consultation-first approach — we assess suitability before recommending treatment
  • Clear complaints process — we take patient feedback seriously

This content is for informational purposes only and does not constitute medical advice. Individual suitability for any treatment is assessed during a consultation. Always seek the guidance of a qualified medical professional with any questions regarding a medical condition or treatment.

Clinical governance

Page last reviewed: 2026-02-10

Reviewed by Dr Selena Langdon, Medical Director (GMC 6159259) — Last reviewed: 2026-02-10

Doctor-Led
CQC Registered
Award-Recognised
Est. 2016

Further Reading & Clinical References

The following external resources provide independent clinical and regulatory information.

Ready to Start Your Journey?

Book a consultation with our expert team today.