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Berkshire Aesthetics is a doctor-led, CQC-registered aesthetic clinic in Maidenhead. All treatments begin with a consultation to assess suitability, medical history, risks and realistic outcomes.

Profhilo vs polynucleotides

Profhilo is generally considered for broad skin hydration and bio-remodelling, while polynucleotides are considered for regenerative skin quality work, including delicate areas in suitable patients. The right choice depends on the concern, treatment area and clinical assessment.

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Quick comparison table for Profhilo vs polynucleotides
ConsiderationProfhiloPolynucleotides
Best forBroad skin quality, hydration and mild laxityRegeneration-focused skin quality, fine lines and delicate areas
Not suitable forPatients needing structural volume replacementPatients wanting immediate volume or tightening
DowntimeUsually minimal; temporary injection bumps can occurUsually minimal; swelling or tenderness can occur
SessionsOften planned as a short course, then maintenanceOften planned as a course with review
Cost considerationsGuide price confirmed on treatment page and at consultationGuide price confirmed on treatment page and at consultation

When we might recommend neither treatment

  • Your medical history or current skin condition makes treatment unsafe.
  • Your goals would be better served by delaying treatment, using skincare first, or seeking medical diagnosis.
  • The expected improvement is unlikely to justify the risk, downtime or cost.

What to ask at consultation

  • Which concern are we treating: skin quality, volume, laxity, texture or muscle activity?
  • What are the realistic benefits and limitations for my anatomy or skin type?
  • What are the main risks, downtime and aftercare requirements?
  • How many sessions might be needed and when would we review progress?

FAQs

Can Profhilo and polynucleotides be combined?

They can be considered together for some patients, but sequencing and suitability should be assessed by a clinician.

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Book a consultation with our expert team today.