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Nasolabial Fold Treatments
Clinical management of nose-to-mouth lines and mid-face ageing
Nasolabial folds — the lines running from the sides of the nose to the corners of the mouth — are a natural facial feature that deepens with age as mid-face volume diminishes and skin loses elasticity. While some depth is normal, deepened folds can create a tired or aged appearance. Treatment often involves addressing the underlying volume loss rather than simply filling the crease directly, which produces a more natural and longer-lasting result.
Aetiology & Contributing Factors
Most skin and aesthetic concerns are multifactorial. Clinical assessment helps identify which contributing factors are most relevant in your case before treatment is selected.
- Age-related loss of mid-face fat volume causing the cheek to descend
- Decline in collagen and elastin reducing skin support
- Gravitational descent of facial soft tissue
- Bone resorption in the maxilla reducing mid-face projection
- Repeated facial expressions deepening the fold over time
- Sun damage and photoageing accelerating skin structural changes
- Genetic factors influencing facial fat distribution and skin elasticity
Clinical Presentation
Presentation varies by skin type, severity and duration. These are common clinical signs we assess during consultation.
- Deep creases running from the nose to the corners of the mouth
- Shadow or fold that is visible at rest, not just when smiling
- Loss of mid-face volume creating a flatter cheek profile
- Asymmetric fold depth — one side deeper than the other
- Marionette lines extending below the mouth corners (often co-occurring)
- A tired or downturned appearance to the lower face
Evidence-Based Treatment Modalities
Treatment selection is individualised following clinical assessment, taking into account disease severity, Fitzpatrick skin type, medical history and patient goals. You can also review our consultation standards before booking.
Dermal Fillers treatment for nasolabial folds
Dermal fillers can be used to directly soften the nasolabial fold or restore mid-face volume that is contributing to fold depth. Treating the cheek and mid-face often produces a more natural result than filling the fold alone. Suitability confirmed during consultation.
Profhilo treatment for nasolabial folds
Profhilo bio-remodelling improves skin quality, hydration and elasticity in the lower face and mid-face. It is effective for mild nasolabial creasing where skin quality rather than volume is the primary concern. Suitability confirmed during consultation.
Ultherapy treatment for nasolabial folds
Ultherapy delivers focused ultrasound to stimulate collagen in the deeper tissue layers, creating a gradual lifting effect in the mid-face that can reduce nasolabial fold depth. Suitability confirmed during consultation.
Why we start with a consultation
Every treatment begins with a medical assessment. We need to understand your medical history, current health, skin condition and concerns before prescribing any procedure. This protects your safety and ensures the treatment is clinically appropriate for you.
During your consultation, Dr Langdon will explain what the treatment can realistically achieve, any risks specific to you, and whether an alternative might be more appropriate.
All bookings are subject to our Booking Conditions.
Not sure what you need?
Try our free AI skin analysis to identify your main concerns and see suggested treatments.
Start free skin analysis →Clinical FAQs: Nasolabial Folds
These answers cover common practical questions. For individual diagnosis and treatment advice, book a medical consultation.
Plan Your Next Step
Use these links to review consultation standards, check treatment pricing, and request a doctor-led assessment.
Clinical Summary
Clinical Governance
- Doctor-led assessment identifies whether nasolabial folds are driven by volume loss, skin laxity or both — each requiring a different treatment strategy
- We often treat the cause (mid-face volume loss) rather than just the symptom (the fold itself) for more natural, longer-lasting results
- Conservative treatment is prioritised — over-filling nasolabial folds can look unnatural, and we aim for balanced facial harmony
Book a Consultation
Request a medical assessment for your nasolabial folds with our clinical team.
Book NowCall 01628 202028Not sure what you need?
Try our free AI skin analysis to identify your main concerns and see suggested treatments.
Start free skin analysis →Related Conditions
Explore related condition pages for differential context and linked treatment options.
Further Reading & Clinical References
The following external resources provide independent clinical and regulatory information.
- Caring for your skin— BAD
This content is for informational purposes only and does not constitute medical advice. Individual suitability for any treatment is assessed during a consultation. Always seek the guidance of a qualified medical professional with any questions regarding a medical condition or treatment.
- CQC registered clinic — regulated and inspected
- Doctor-led clinical oversight by Dr Selena Langdon (GMC 6159259)
- Complaints process and patient rights
Page last reviewed: March 2026
Reviewed by Dr Selena Langdon, Medical Director (GMC 6159259) — Last reviewed: February 2026
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