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Profhilo vs Structura
Both made by IBSA, both use hyaluronic acid — but designed for different skin concerns
Book ConsultationProfhilo and Structura are both injectable hyaluronic acid treatments from IBSA, but they serve distinct purposes. Profhilo is a bio-remodelling treatment that floods the skin with hydration while stimulating collagen and elastin for improved skin quality. Structura takes this further with NAHYCO Hybrid Technology, delivering deeper structural support for lifting and firming lax skin. Understanding the difference helps you choose the right treatment — or whether a combination of both delivers the best outcome.
NAHYCO stabilised HA for bio-remodelling — stimulates collagen and elastin for hydration and elasticity
Best For
- • Overall skin hydration and radiance
- • Fine lines and crepey skin texture
- • Restoring a healthy glow to dull, dehydrated skin
- • Face, neck, décolletage and hands
- • Patients wanting a natural improvement in skin quality
Not Suitable For
- • Volume restoration or facial contouring
- • Significant skin laxity or sagging
- • Patients expecting dramatic lifting results
- • Active skin conditions in the treatment area
- • Those seeking a single-session protocol (requires 2 sessions)
Results Timeline
2–4 weeks after second session
Sessions
2 sessions 4 weeks apart; maintenance every 6–9 months
Starting Price
From £350
Downtime
Minimal — small bumps at injection points resolve within 24 hours
Next-generation NAHYCO Hybrid Technology for deeper tissue remodelling, lifting and firming
Best For
- • Skin laxity on the face and neck
- • Jawline definition and lower face firming
- • Deeper dermal remodelling beyond surface hydration
- • Patients wanting structural improvement alongside skin quality
- • Those who have had Profhilo and want to progress to a lifting treatment
Not Suitable For
- • Patients whose primary goal is pure hydration or glow
- • Very fine superficial lines without underlying laxity
- • Volume loss requiring dermal filler
- • Active infection or inflammation in the treatment area
- • Patients who have not yet tried bio-remodelling and may benefit from Profhilo first
Results Timeline
Progressive improvement over 4–8 weeks
Sessions
2 sessions 4 weeks apart; maintenance every 6–12 months
Starting Price
From £450
Downtime
Minimal — mild swelling or tenderness at injection sites for 24–48 hours
When We Recommend Each Treatment
Choose Profhilo if
- Your main concern is dehydrated, dull or crepey skin
- You want improved skin quality, radiance and fine line reduction
- You are new to bio-remodelling treatments
- Your skin has not yet developed significant laxity
Choose Structura if
- You have noticeable skin laxity on the face or neck
- You want firming and lifting alongside skin quality improvement
- You have had Profhilo before and want to address sagging
- Jawline definition is a priority
Consider combining both when
- You want hydration and glow from Profhilo plus structural lifting from Structura
- Different areas of your face have different needs — surface quality in some, laxity in others
- Your clinician recommends a phased approach starting with Profhilo then progressing to Structura
Frequently Asked Questions
What is the main difference between Profhilo and Structura?
Both are made by IBSA and use hyaluronic acid, but they target different concerns. Profhilo focuses on hydration, elasticity and overall skin quality through bio-remodelling. Structura uses a next-generation NAHYCO Hybrid Technology designed to provide deeper structural support, lifting and firming for lax skin.
Can I have both Profhilo and Structura?
Yes. Many patients benefit from combining both treatments. Profhilo addresses hydration and surface skin quality while Structura provides deeper lifting and firming. Your clinician will advise on the best sequence and timing based on your individual concerns.
Which is better for the neck?
Both can be used on the neck. Profhilo is excellent for improving neck skin quality, hydration and crepiness. Structura is better suited when there is noticeable skin laxity or sagging on the neck that requires structural support. A consultation will determine which is most appropriate.
Is Structura newer than Profhilo?
Yes. Structura is the latest addition to the IBSA injectable range, building on the success of Profhilo. It was developed to address concerns that go beyond hydration — specifically skin laxity and the need for deeper tissue remodelling and lifting.
Do both treatments require 2 sessions?
Yes. Both Profhilo and Structura follow an initial protocol of 2 sessions spaced 4 weeks apart. This allows the treatment to build its full effect. Maintenance sessions are then recommended every 6 to 12 months depending on individual response.
Not Sure Which Treatment Is Right?
Book a consultation to assess your skin and discuss whether Profhilo, Structura or a combination of both is the best approach for your goals.
Book Your ConsultationWhich is right for you?
The best treatment depends on your individual concerns, skin condition, and goals. Here are some general considerations:
- Choose Profhilo if your main concern is dehydrated, dull or crepey skin and you want improved radiance and elasticity
- Choose Structura if you have noticeable skin laxity and want firming, lifting and deeper structural remodelling
- Consider combining both if you want the hydration benefits of Profhilo alongside the lifting effect of Structura
- If you are unsure, a consultation will help clarify which approach addresses your specific concerns
This is general guidance only — treatment suitability is always confirmed during a clinical consultation.
Doctor-led approach
- Treatment suitability is assessed by our doctors or advanced aesthetic practitioners during a clinical consultation, depending on the treatment
- Prescribing responsibility sits with Dr Selena Langdon (GMC 6159259)
- No same-day injectable treatments for new patients
- Read our full Consultation & Safety Standards
- CQC registered clinic — regulated and inspected
- Doctor-led clinical oversight by Dr Selena Langdon (GMC 6159259)
- Complaints process and patient rights
Reviewed by Dr Selena Langdon, Medical Director (GMC 6159259) — Last reviewed: February 2026
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