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Profhilo vs Dermal Fillers
Comparing bio-remodelling with volumising injectable treatments
Book ConsultationProfhilo and dermal fillers are both hyaluronic acid-based injectables, but they serve fundamentally different purposes. Profhilo improves overall skin quality through bio-remodelling, while fillers restore lost volume and define facial contours. Understanding this distinction is key to choosing the right treatment — or knowing when both are needed.
Bio-remodelling — stimulates collagen and elastin production
Best For
- • Skin laxity and firmness
- • Crepey skin texture
- • Neck and décolletage
- • Overall skin quality
- • Early signs of ageing
Not Suitable For
- • Adding volume to cheeks or lips
- • Deep fold correction
- • Jawline definition
- • Immediate structural change
Duration
6-12 months
Results Visible
4-8 weeks
Starting Price
From £300 per session
Downtime
Minimal — small bumps for 24-48 hours
Volume replacement — adds structure using hyaluronic acid gel
Best For
- • Cheek volume restoration
- • Lip enhancement
- • Jawline definition
- • Nasolabial fold softening
- • Under-eye hollows
Not Suitable For
- • Improving skin quality or texture
- • Treating crepey skin
- • Skin tightening
- • Widespread fine lines
Duration
6-18 months
Results Visible
Immediate
Starting Price
From £250 per area
Downtime
Mild swelling and bruising for 3-7 days
Frequently Asked Questions
What is the main difference between Profhilo and fillers?
Profhilo improves skin quality (hydration, firmness, elasticity) without adding volume. Fillers add volume and structure to specific areas. They address different concerns and are often complementary rather than competing treatments.
Can I have both Profhilo and fillers?
Yes, this is a common combination. Profhilo addresses skin quality while fillers restore structure and volume. Your doctor will advise on sequencing — typically Profhilo is completed first, with fillers added 4-6 weeks later.
Which is better for anti-ageing?
It depends on your primary concern. If your skin has lost firmness and looks crepey, Profhilo may be more beneficial. If you have lost volume in your cheeks, lips or jawline, fillers are more appropriate. Many patients benefit from both.
Which lasts longer?
Dermal fillers generally last longer (6-18 months depending on product and area) compared to Profhilo (6-12 months). However, Profhilo creates lasting improvements in skin quality that build with repeated courses.
Which is safer?
Both are very safe when performed by experienced doctors. Fillers carry slightly higher risks in certain areas (e.g. under the eyes, lips) due to the vascular anatomy. Your doctor will discuss specific risks during consultation.
Not Sure Which Treatment Is Right for You?
Book a consultation with Dr Langdon to assess your skin and discuss whether Profhilo, fillers or a combination would best address your concerns.
Book Your ConsultationWhich is right for you?
- Choose Profhilo if your skin has lost firmness, feels crepey or dehydrated, and you want an overall quality improvement
- Choose dermal fillers if you have lost volume in specific areas like cheeks, lips or jawline, or want to soften deep folds
- Consider both if you have volume loss alongside declining skin quality — this is common from the mid-40s onwards
This is general guidance only — treatment suitability is always confirmed during a clinical consultation.
Doctor-led approach
- Treatment suitability is assessed by a doctor during a clinical consultation
- Prescribing responsibility sits with Dr Selena Langdon (GMC 6159259)
- No same-day injectable treatments for new patients
- Read our full Consultation & Safety Standards
- CQC registered clinic — regulated and inspected
- Doctor-led clinical oversight by Dr Selena Langdon (GMC 6159259)
- Complaints process and patient rights
Reviewed by Dr Selena Langdon, Medical Director (GMC 6159259) — Last reviewed: February 2026
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