At Berkshire Aesthetics, we are proud to offer our patients the most advanced and scientifically proven skin rejuvenation treatments. One of the most exciting innovations in regenerative aesthetics today is polynucleotide treatment. This cutting-edge injectable therapy harnesses the body’s natural ability to repair and regenerate the skin at a cellular level.
Whether you’re looking to restore youthful radiance, reduce the appearance of fine lines, or improve overall skin texture and elasticity, polynucleotides could be the ideal solution. In this blog post, we will explain how the treatment works, its benefits, who it is suitable for, and what to expect during your journey with us in Maidenhead, Berkshire.
Polynucleotides are chains of nucleotides, the building blocks of DNA and RNA. When used in aesthetics, they are derived from purified salmon DNA, chosen for its biocompatibility with human skin. These biologically active molecules stimulate tissue regeneration, support fibroblast proliferation, and increase the production of collagen and elastin, leading to healthier, firmer, and more hydrated skin.
Unlike hyaluronic acid-based fillers that primarily provide volume and hydration, polynucleotide treatments focus on regeneration, encouraging the skin to repair itself naturally over time.
Polynucleotides are delivered into the skin via a series of micro-injections, administered precisely by one of our experienced medical practitioners. Once injected, they begin to work by:
Stimulating fibroblasts, which are the cells responsible for producing collagen and elastin.
Improving microcirculation, which enhances oxygen and nutrient delivery to the tissues.
Reducing inflammation and oxidative stress in the skin, leading to a more even and calm complexion.
Hydrating the skin from within by increasing the skin’s ability to retain moisture.
This holistic, regenerative process leads to long-term improvements in skin health, rather than just temporary cosmetic changes.
Polynucleotide injections are highly versatile and can be used across various areas of the face and body. At Berkshire Aesthetics, we recommend this treatment for patients experiencing:
Fine lines and early signs of ageing
Dehydrated or dull skin
Acne scarring and textural irregularities
Loss of skin elasticity
Redness and sensitivity due to inflammation
Under-eye hollows and dark circles
Stretch marks or sun-damaged skin
Whether used alone or in combination with other skin boosters such as Profhilo, polynucleotides offer a powerful solution for skin rejuvenation.
At Berkshire Aesthetics, we use only the highest-quality polynucleotide products, supported by robust clinical research. The leading brands we offer include:
Ameela® (formerly known as Nucleofill) – Designed to improve skin elasticity and density, particularly around the eyes and cheeks.
Plinest® – A well-established polynucleotide range derived from Italian biotech, ideal for treating aged or damaged skin.
Purasomes® – A newer generation combining polynucleotides with antioxidants for an enhanced anti-inflammatory and regenerative effect.
Each product is carefully selected and tailored to your individual needs during your consultation.
Polynucleotide treatments are safe for multiple areas of the face and body. Standard treatment zones include:
Face – To smooth fine lines, improve tone, and boost radiance.
Periorbital (eye) area – To reduce hollowness, dark circles, and signs of fatigue.
Neck & décolletage – For firming and revitalisation.
Scalp – To support hair growth and scalp health in both men and women.
Hands – To restore volume and improve skin texture.
Stretch marks and scars – To support regeneration in damaged skin tissue.
Your journey starts with a personalised consultation at our clinic in Maidenhead, where one of our experienced medical team members will assess your skin and discuss your goals. We will determine the most suitable product and number of sessions for optimal results.
The treatment itself is quick and well-tolerated. Using a fine needle or cannula, small amounts of the polynucleotide solution are injected into the target area. Numbing cream is applied beforehand to ensure comfort.
There may be minor redness, swelling, or small bruises at the injection sites. These usually resolve within 24 to 48 hours. Because polynucleotides are biocompatible, side effects are rare and mild.
While some improvement may be seen after one treatment, we generally recommend a course of three sessions, spaced 2–4 weeks apart, for best results. Maintenance treatments every 4–6 months help to preserve the effects over time.
Here’s why patients across Berkshire, Marlow, Windsor, and Beaconsfield are turning to polynucleotide skin therapy:
Biostimulatory Effect – Promotes natural skin regeneration rather than masking concerns.
Long-Term Improvement – Results improve gradually and last for several months.
Hydration and Elasticity – Deep moisturisation and skin firming from within.
Safe and Natural – Minimal risk of adverse reactions.
Complementary to Other Treatments – Works beautifully alongside anti-wrinkle injections or energy-based treatments, such as Morpheus8.
Polynucleotides are suitable for both men and women of all skin types and ages. The treatment is ideal for:
Individuals with early to moderate signs of skin ageing
Those looking for a natural, regenerative solution to dull or damaged skin
People who have not responded well to traditional skin boosters
Patients wanting to improve delicate areas like under the eyes or the neck
Our medical team will guide you through a thorough consultation to ensure this treatment is proper for you.
To maximise your aesthetic results, polynucleotides can be combined with:
Profhilo – For added hydration and volume
Anti-wrinkle injections – To target dynamic lines alongside regenerative therapy
Morpheus8 – Radiofrequency microneedling to improve deeper skin structures
LED Light Therapy – To accelerate healing and enhance anti-inflammatory benefits
We will create a customised treatment plan tailored to your goals and skin condition.
Yes, they are derived from natural sources and purified to remove any proteins that could cause an immune reaction. They are considered very safe and have been used in medical fields such as ophthalmology and wound healing for decades.
You may start to notice improved hydration and glow within the first week. Collagen stimulation and tissue repair take time, so optimal results are usually visible after 4 to 8 weeks following your final treatment.
Polynucleotides are not designed to replace dermal fillers. Instead, they complement them by improving skin quality and resilience. If you’re looking for volume, we may recommend a combination approach.
At Berkshire Aesthetics, our medical-led approach ensures GMC-registered doctors carry out all injectable treatments with extensive experience in aesthetic medicine. We believe in delivering natural, subtle results that enhance your skin’s health and radiance.
Our clinic is conveniently located in Maidenhead, serving patients from Marlow, Beaconsfield, Windsor, Ascot, and beyond. We offer bespoke care, advanced products, and the latest in regenerative skin technology to help you look and feel your best.
If you’re ready to experience the regenerative power of polynucleotides, we invite you to book a consultation with our expert team. Whether you’re interested in a standalone treatment or a personalised combination approach, we’ll guide you every step of the way.
To book a consultation or for any questions, please complete the form below or call our clinic on 01628 202028. (Please note that calls will not be accepted from private or blocked numbers.)
Please note that a consultation fee must be paid at the time of bookin to secure appointmentsg. This fee is redeemable against the cost of any treatment completed within 28 days of the appointment. Please note that the fee cannot be used to purchase products. Patients who fail to attend their appointments or do not provide the required notice to change or cancel their appointments agree to pay the required cancellation fee.
Before booking, all patients are requested to review the Booking Conditions, including our cancellation policy and agree to adhere to these terms.
N.B. Any prices quoted before an in-person consultation with a doctor or practitioner are given as a guide only.
Is your clinic near me?
We serve patients from Berkshire, Buckinghamshire, Oxfordshire, and London and are within easy reach of:
Ascot – Beaconsfield – Bracknell – Bray – Cookham – Henley – Maidenhead – Marlow – Reading – Sonning – Stoke Poges – Sunningdale – Wentworth – Windsor
T. 01628 202028
E. info@berkshireaesthetics.com
A. Furze Platt Road, Maidenhead, Berkshire SL6 6PR
Please note that the results of medical treatment and patient experiences may vary. Outcomes cannot be guaranteed and our services are the provision of treatment with no guarantee of the outcome provided. As our treatments are medical procedures and carry risks of complications and a full consultation (including the taking of detailed medical history) is required prior to any treatment being provided. Any prices quoted prior to a face-to-face consultation are given as a guide only. All calls are recorded for training and monitoring purposes. Photos of the treated area must be taken prior to, during, and following any treatment. Treatment cannot proceed without images being captured and is for the protection of the clinic, the patient, and for insurance purposes.
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